Ownership Profile

Shareholder Breakdown

Shareholder Holders Value ($MM) % O/S Shares
Institution 246 1,795.06 85.51 49,059,309
Mutual Fund 221 735.39 33.14 19,013,630
Insider 2 0.12 0.01 3,808

Institutional Shareholder Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 167 780.99 34.29 19,672,855
Sellers 84 -595.29 31.42 -18,023,147
Net -- 185.69 2.87 1,649,708

Institutional Shareholder Concentration

Value ($MM) % O/S Shares
Total Inst. 1,795.06 85.51 49,059,309
Top 10 Inst. 763.53 39.23 22,507,406
Top 20 Inst. 1,138.82 56.41 32,360,985
Top 50 Inst. 1,574.71 75.63 43,386,723

Institutional Shareholder Style

Holders Value ($MM) % Inst Shares Shares
Growth 44 415.71 16.98 9,742,912
Aggressive Growth 5 166.67 6.83 3,918,811
Core Growth 25 136.29 5.55 3,183,260
Growth 14 112.75 4.60 2,640,841
Income 3 6.38 0.26 150,091
Income Value 1 6.09 0.25 142,062
Yield 2 0.30 0.01 8,029
Index 22 450.99 18.38 10,542,007
Momentum 1 21.41 0.87 499,855
Other 98 670.75 32.59 18,699,358
Broker Dealer 21 44.02 1.79 1,027,553
GARP 29 132.76 5.40 3,099,082
Hedge Fund 41 395.87 19.04 10,920,536
Sector Specific 2 76.43 3.11 1,784,170
Specialty 2 3.33 0.14 77,678
VC/Private Equi 3 18.34 3.12 1,790,339
Value 26 159.14 6.58 3,776,853
Core Value 19 149.42 6.19 3,549,915
Deep Value 7 9.72 0.40 226,938

Top Holders: Institutional Investor

Holder Shares Held % O/S Share Change Filing Date
The Vanguard Group, Inc. 3,792,662 6.61 1,884,560 9/30/18
BlackRock Institutional Trust Company, N.A. 3,631,559 6.33 918,499 9/30/18
Fred Alger Management, Inc. 3,371,372 5.88 1,401,188 9/30/18
DexCom Inc 2,500,000 4.36 2,500,000 2/13/18
Two Sigma Investments, LP 1,922,891 3.35 1,767,133 9/30/18
Federated Global Investment Management Corp. 1,608,200 2.80 -1,048,300 9/30/18
Frontier Capital Management Company, LLC 1,456,378 2.54 -1,177,078 9/30/18
Lord, Abbett & Co. LLC 1,445,705 2.52 952,506 9/30/18
Corrib Capital Management L.P. 1,411,836 2.46 -3,088,164 4/30/18
Delphi Ventures L.P. 1,366,803 2.38 1,000,000 3/31/18
Blickenstaff (Kim D) 1,236,494 2.16 750,000 3/31/18
Emerald Advisers, Inc. 1,232,572 2.15 -275,502 9/30/18
State Street Global Advisors (US) 1,150,037 2.00 -63,876 9/30/18
TimesSquare Capital Management, LLC 1,092,500 1.90 1,092,500 9/30/18
Redmile Group, LLC 1,069,670 1.86 1,069,670 9/30/18
Ardevora Asset Management LLP 863,396 1.50 863,396 9/30/18
Schonfeld Strategic Advisors LLC 829,264 1.45 -207,336 9/30/18
Point72 Asset Management, L.P. 827,999 1.44 -411,601 9/30/18
Eagle Asset Management, Inc. 790,647 1.38 790,647 9/30/18
Millennium Management LLC 761,000 1.33 15,559 9/30/18
OrbiMed Advisors, LLC 714,500 1.25 -974,500 9/30/18
Goldman Sachs & Company, Inc. 622,490 1.09 611,390 9/30/18
Northern Trust Investments, Inc. 598,741 1.04 107,126 9/30/18
Geode Capital Management, L.L.C. 585,672 1.02 186,134 9/30/18
Broadfin Capital, L.L.C. 573,079 1.00 2,481 9/30/18
Hitchwood Capital Management LP 570,000 0.99 570,000 9/30/18
Armistice Capital LLC 531,354 0.93 531,354 10/13/17
Friess Associates LLC 499,855 0.87 391,855 9/30/18
Hood River Capital Management LLC 448,690 0.78 448,690 9/30/18
Baillie Gifford & Co. 434,700 0.76 434,700 9/30/18
Deutsche Asset Management Americas 431,543 0.75 289,677 9/30/18
Renaissance Technologies LLC 395,594 0.69 189,230 9/30/18
AQR Capital Management, LLC 378,510 0.66 373,256 9/30/18
CastleArk Management, LLC 351,850 0.61 -103,320 9/30/18
Wasatch Advisors, Inc. 347,845 0.61 -205,743 9/30/18
Citadel LLC 319,706 0.56 134,942 9/30/18
Charles Schwab Investment Management, Inc. 301,726 0.53 206,040 9/30/18
Marshall Wace LLP 287,296 0.50 287,296 9/30/18
Deerfield Management Company, L.P. 283,115 0.49 -2,290,190 9/30/18
First Light Asset Management, LLC 263,883 0.46 -1,640,377 9/30/18
TPG Capital, L.P. 249,620 0.44 -- 9/30/18
T. Rowe Price Associates, Inc. 246,892 0.43 246,892 9/30/18
Cavanaugh (Kevin M) 239,100 0.42 239,100 4/30/18
Oberweis Asset Management, Inc. 225,050 0.39 225,050 9/30/18
Driehaus Capital Management, LLC 211,860 0.37 166,860 9/30/18
Columbia Wanger Asset Management, LLC 198,986 0.35 -141,650 9/30/18
Nuveen LLC 198,090 0.35 11,273 9/30/18
HLM Venture Partners 173,916 0.30 -- 3/31/18
Goldman Sachs Asset Management (US) 173,095 0.30 170,505 9/30/18
BlackRock Investment Management, LLC 168,980 0.29 19,702 9/30/18

* Insider values reflect direct beneficial ownership.

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